Cytoxan (Cyclophosphamide) Information

The active ingredient in Cytoxan is:

• Cyclophosphamide: 50 mg, 100 mg, or 200 mg per tablet (oral form) or in injectable form

Other inactive ingredients may include:

• Lactose
• Magnesium stearate
• Sodium chloride

Common side effects include:

• Hair loss
• Nausea and vomiting
• Fatigue
• Decreased appetite
• Increased risk of infection

Serious side effects requiring immediate medical attention:

• Severe allergic reactions (rash, swelling, difficulty breathing)
• Signs of bleeding (unusual bruising, nosebleeds, or blood in the urine)
• Severe infection symptoms (fever, chills, sore throat)
• Signs of liver problems (yellowing of the skin or eyes, dark urine)
• Severe abdominal pain

Cytoxan is usually administered intravenously (IV) by a healthcare professional, although it is also available in oral tablet form for certain conditions. The dosage and frequency depend on the specific condition being treated and the patient's overall health.

Important considerations:

• Cytoxan is typically given in cycles, with breaks between doses to allow the body to recover.
• Follow your doctor’s instructions carefully to ensure the correct dosage and avoid adverse effects.
• Drink plenty of fluids during treatment to help protect the bladder from damage caused by the drug.

Cytoxan may interact with other medications, so it is important to inform your doctor of all the drugs you are taking, including over-the-counter medications, supplements, and herbal remedies.

Common interactions include:

• Other chemotherapy agents: May increase the risk of severe side effects or infections.
• Blood thinners (e.g., warfarin): May increase the risk of bleeding.
• Vaccines: Live vaccines should be avoided, as Cytoxan may weaken the immune system and increase the risk of infections.

Cytoxan begins working soon after it is administered, but the full effects can take weeks or even months to be evident, depending on the condition being treated. For cancers, it may take several cycles of treatment to see significant improvements. In autoimmune diseases, the effects can vary depending on the individual and the severity of the condition.

If you experience any of the serious side effects listed above, such as severe allergic reactions, signs of bleeding, or signs of infection, contact your doctor immediately or seek emergency medical attention. Regular monitoring through blood tests is often required during treatment to track potential side effects.